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Kantarjian et al53 assessed the efficacy and protection of dasatinib, as in contrast with imatinib, for the initial-line remedy of CML-CP. Five hundred and nineteen clients with freshly diagnosed CML-CP were being randomly assigned to get dasatinib at a dose of 100 mg once each day (259 sufferers) or imatinib at a dose of 400 mg after day-to-day (2